Dapagliflozin and Mode of Death in Heart Failure With Improved Ejection Fraction: A Post Hoc Analysis of the DELIVER Trial

O Vardeny, AS Desai, PS Jhund, JC Fang… - JAMA …, 2024 - jamanetwork.com
death in patients with HFimpEF to a similar extent as in those … In this post hoc report, we
evaluated the mode of death of … of dapagliflozin with reductions in cause-specific death in …

[HTML][HTML] Dapagliflozin across the range of ejection fraction in patients with heart failure: a patient-level, pooled meta-analysis of DAPA-HF and DELIVER

PS Jhund, T Kondo, JH Butt, KF Docherty… - Nature medicine, 2022 - nature.com
… to Improve the LIVEs of Patients With Preserved Ejection … of dapagliflozin on mortality and
the composite of death from … at higher ejection fractions reported in the EMPEROR trials 12 , …

… safety of dapagliflozin in patients with heart failure with mildly reduced or preserved ejection fraction by baseline glycaemic status (DELIVER): a subgroup analysis …

SE Inzucchi, BL Claggett, M Vaduganathan… - The Lancet Diabetes & …, 2022 - thelancet.com
fraction, oral dapagliflozin improved heart failure outcomes to a … risk of worsening heart failure
or cardiovascular death by 18… We also assessed (post hoc) efficacy of dapagliflozin within …

… rate after dapagliflozin in heart failure with mildly reduced or preserved ejection fraction: a prespecified secondary analysis of the DELIVER randomized clinical trial

FR Mc Causland, BL Claggett, M Vaduganathan… - JAMA …, 2024 - jamanetwork.com
… with cardiovascular (cardiovascular death or heart failureanalysis of the Dapagliflozin
Evaluation to Improve the Lives … level in this trial, 24 we evaluated a post hoc kidney composite …

… , outcomes, and treatment response with dapagliflozin across the range of ejection fraction in patients with heart failure: insights from DAPA-HF and DELIVER

X Wang, M Vaduganathan, BL Claggett, SM Hegde… - Circulation, 2023 - Am Heart Assoc
… recurrent HF hospitalization and cardiovascular death), as well as improved KCCQ scores,
… variability of results with different post hoc EF cut points in the EMPEROR trials (eg, benefit in …

… -free and overall survival with dapagliflozin in patients with heart failure and reduced ejection fraction: an exploratory analysis of a phase 3 randomized clinical trial

KF Docherty, PS Jhund, B Claggett, JP Ferreira… - JAMA …, 2021 - jamanetwork.com
… In DAPA-HF, dapagliflozin also improved symptoms and … In addition to usual limitations of
post hoc analyses of trials, there … of DELIVER and DETERMINE (trials using dapagliflozin) in …

… men and women with heart failure with reduced ejection fraction: a prespecified analysis of the dapagliflozin and prevention of adverse outcomes in heart failure trial

JH Butt, KF Docherty, MC Petrie, M Schou… - JAMA …, 2021 - jamanetwork.com
… , cardiovascular death, and all-cause death and improved symptoms, … outcomes by sex was
done post hoc. The proportion of … These findings provide further support for dapagliflozin as a …

Effect of dapagliflozin on worsening heart failure and cardiovascular death in patients with heart failure with and without diabetes

MC Petrie, S Verma, KF Docherty, SE Inzucchi, I Anand… - Jama, 2020 - jamanetwork.com
… to enroll patients with heart failure and reduced ejection fraction. … In a post hoc sensitivity
analysis, we included trial site as an … was not improved significantly by dapagliflozin overall). In …

Time to clinical benefit of dapagliflozin and significance of prior heart failure hospitalization in patients with heart failure with reduced ejection fraction

DD Berg, PS Jhund, KF Docherty, SA Murphy… - JAMA …, 2021 - jamanetwork.com
… treatment approaches to improve outcomes following HF … First, this was a post hoc analysis
of a clinical trial; therefore, … in the DAPA-HF trial and the DELIVER trial, as well as fees for …

Efficacy of dapagliflozin on renal function and outcomes in patients with heart failure with reduced ejection fraction: results of DAPA-HF

PS Jhund, SD Solomon, KF Docherty, HJL Heerspink… - Circulation, 2021 - Am Heart Assoc
… Last, our data do not provide any further information on how the … , and symptoms were
improved by dapagliflozin, in comparison … : a post hoc analysis of two randomised controlled trials.…